CAS No. 75-05-8 | Catalog No. 655668
Acetonitril;acetonitril(german;dutch) ;CH3CN;Cyanomethan;Acetonitrilo;CH3CN;cianometano;cianuro di metile;cyanomethane;Cyanure de methyl;etanonitrile;Ethane nitrile;Ethanenitrile;Ethyl nitrile;MeCN;Methane; cyano-;methyl cyanide;Methylidyne; cyano-
||organic solvents: soluble(lit.)
It may be used as a solvent to prepare:
• 1;2-Azidoalcohols and 1;2-azidoamines via cerium(III) chloride assisted ring opening of epoxides and aziridines by sodium azide.
• Cyano-bearing indolinones by oxidative arylalkylation of olefins in the presence of palladium catalyst.
It may also be used as a reactant to synthesize:
• Bis (diphenylphosphino) by reacting with n-butyllithium and then with chlorodiphenylphosphine.
• β-Acetamido ketones via coupling reaction with ketones or ketoesters and aldehydes in the presence of cobalt(II) chloride.
The product contains 0.1%v/v trifluoroacetic acid. This pre-blended mobile phase solvent is of high purity that reduces time-consuming preparation and prevents instrument downtime because of impure mobile phases. Trifluoroacetic acid mobile phase system is generally employed for peptide separation. (MeCN); an organic solvent has low viscosity; high elution strength and is UV transparent at low wavelength. Trifluoroacetic acid (TFA) is commonly used as a mobile phase additive. It is a volatile acid that forms hydrophobic negatively charged trifluoroacetate ion.