A Division Of
4-methylphenyl isothiocyanate
CAS No. 622-59-3 | Catalog No. 200182
Synonyms
P-TOLYL ISOTHIOCYANATE;TIMTEC-BB SBB008290;isothiocyanicacid;4-tolylester ;p-Tolylisothiocyanate;97%;p-Tolyl isothiocyanate;99%;p-Tolyl isothiocyanate 97%
Properties
| Boiling Point | 237 °C(lit.) |
| Melting Point | 25-26 °C(lit.) |
Application
It has been used:
• in the preparation of 6-[1-amino-3-(p-tolyl)-thiourea]-2-ethylbenzo[de]isoquinoline-1;3-dione
• as capping agent to cap the N-terminal ends of polypeptides
• it is also used as pharmaceutical intermediate.
General Description
It reacts with 6-hydroxy-2;4;5-triaminopyrimidine or with 4;5;6-triaminopyrimidine in DMF and triethylamine to yield 2;4-diamino-5-(p-tolylthioureido)aminopyrimidin-6-one and 4;6-diamino-5-(tolylthioureido)aminopyrimidine; respectively.
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