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4-methylphenyl isothiocyanate

CAS No. 622-59-3 | Catalog No. 200182


Synonyms
P-TOLYL ISOTHIOCYANATE;TIMTEC-BB SBB008290;isothiocyanicacid;4-tolylester ;p-Tolylisothiocyanate;97%;p-Tolyl isothiocyanate;99%;p-Tolyl isothiocyanate 97%


Properties

Boiling Point 237 °C(lit.)
Melting Point 25-26 °C(lit.)

Application
It has been used: • in the preparation of 6-[1-amino-3-(p-tolyl)-thiourea]-2-ethylbenzo[de]isoquinoline-1;3-dione • as capping agent to cap the N-terminal ends of polypeptides • it is also used as pharmaceutical intermediate.


General Description
It reacts with 6-hydroxy-2;4;5-triaminopyrimidine or with 4;5;6-triaminopyrimidine in DMF and triethylamine to yield 2;4-diamino-5-(p-tolylthioureido)aminopyrimidin-6-one and 4;6-diamino-5-(tolylthioureido)aminopyrimidine; respectively.

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