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N-(trimethylsilyl)imidazole

CAS No. 18156-74-6 | Catalog No. 655391


Synonyms
1-(trimethylsilyl)-1h-imidazol ;1-(trimethylsilyl)-imidazol ;1-Imidazolyltrimethylsilane;CT3600;Imidazole; 1-(trimethylsilyl)-;Imidazole; N-(trimethylsilyl)-;N-(Trimethylsilyl)imidazol


Properties

Boiling Point 93-94 °C14 mm Hg(lit.)
Form Liquid
Melting Point -42 °C

Application
It acts as a silylating agent for alcohols; carbohydrates and 1;3-dicarbonyl compounds. It is a derivatization reagent used for selective silylation of hydroxyl groups and carboxylic acid without affecting the amino group. It employed as an intermediate for the synthesis of imidazole derivatives. It plays an essential role to synthesize polysubstituted chiral spirotetrahydropyrans. It is also used in the quantification of pintol after derivatization by gas chromatography/ mass spectrometry. TMSI was used for derivatization of carbohydrates into trimethylsilyl ethers. It was also used to synthesize polysubstituted chiral spirotetrahydropyrans and as silylating reagent for the protection of hydroxyl groups in the presence of amine functionalities. Silylating reagent for the protection of hydroxyl groups in the presence of amine functionalities.

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