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phenyl isothiocyanate

CAS No. 103-72-0 | Catalog No. 200332


Synonyms
Phenyl isothiocyanat;Isothiocyanatobenzene; PITC;PITC (Phenylisothiocyanate);Phenyl isothiocyanate; for sequential analysis


Properties

Boiling Point 218 °C(lit.)
Form liquid
Melting Point −21 °C(lit.)
Solubility water: insoluble

Application
It acts as a derivatizing reagent for primary and secondary amines. It is used in sequencing peptides by Edman degradation and in amino acid analyses by HPLC. It is used for derivatizing N-terminal amino acids of proteins for automated sequential analysis. It is a synthon for dithiadiazafulvalenes. Derivatizing reagent for primary and secondary amines. Used in sequencing peptides by Edman degradation and in amino acid analyses by HPLC. It may be employed as a derivatization reagent for high-performance liquid chromatographic (HPLC) analysis of various amphetamine derivatives in body fluids for fore nsic purposes. When modified with polyethylene glycol (PEG); it can be used as a reagent for PEGylation of protein using human serum albumin as a model protein.


General Description
It is an aromatic isothiocyanate. It participates in dehydration reactions of alcohols. It is widely used for synthesis of various biologically important heterocyclic compounds.

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